"Me too" email chains
This may happen to any big or medium size company: the "me too" email chain.
Use your imagination and visualize what an email server can feel in the following situation. An email is sent to a distribution group. Let's say group is rather large, 3000 recipients. There is one reply from an employee: "Please remove me from this distrubition list" sent to the sender and everyone else on the group (Reply to All). Another email from another employee: "me too" as a reply to the previous email, and so on, so on...
Do some math now: 2 emails make 6000 messages, 10 emails 30,000 messages. But 10 emails it's only 0.33% of the whole recipients group. Let only 10% of company answer ... your email server is gone for hours.
In Exchange it's very simple to limit who can send email to groups. A few clicks and it's done. I would suggest every Exchange admin to consider such manoeuvre for any distribution group bigger than 100 users.
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