http://blogs.technet.com/dhitchen/archive/2007/09/10/softgrid-applications-can-a-softgrid-application-be-infected-by-a-virus-or-malware.aspxThere is a simple answer to this, and of course, a more complex one. Simple answer. No. The virtual application is read only and cannot be infected once it has been sequenced. Complex answer. There are several places a virus or malware can be introduced,en-USCommunityServer 2.1 SP1 (Build: 61025.2)