http://blogs.technet.com/b/systemcenterpfe/archive/2012/11/29/system-center-2012-configuration-manager-antivirus-exclusions.aspxI have seen this question asked and answered in some articles and blog posts, however, after teaching the Concepts and Admin Workshop for the new version of the product recently, and getting more familiar with the new Endpoint Protection feature in Systemen-USTelligent Evolution Platform Developer Build (Build: 5.6.50428.7875)