Arpan Shah, Product Manager for MCMS and SharePoint has written a nice article on his blog about how to get ready for Office "12": http://blogs.msdn.com/arpans/archive/2005/11/24/496759.aspx
He quoted me a couple of times pointing to my blog. For your convenience below are direct links to the articles Arpan was refering to.
Regarding direct access to the database or modifying the database with undocumented API (which has the same impact from a support side):
About MCMS 2002 Service Pack 2 articles:
About MCMS 2002 Navigation and Membership Providers for ASP.NET 2.0: