I have listed below which Microsoft technologies are supported by PTC Windchill with the release of 10.0. There is a virtual event describing its feature on May 10th, 2011, you may register here.

Architecture Tier

Product

Operating System

Client Platform

IE 7
IE 8
Office 2003
Office 2007
Project 2007
Outlook 2007

Windows XP Professional (32 +64 bit)
Windows 7 (32 +64 bit)
Windows Vista (32 +64 bit)
Windows Server 2003 (32+64 bit)
Windows Server 2008  (32+64 bit)
Windows Server 2008 R2 (64 bit)

Web Server

IIS 6
IIS 7
IIS 7.5

Windows Server 2003 SP1 (64 bit) 
Windows Server 2008 (64 bit) 
Windows Server 2008 R2 (64 bit) 

Directory Server

Active Directory 2003
Active Directory 2008

Windows Server 2003 SP1 (64 bit) 
Windows Server 2008 (64 bit) 
Windows Server 2008 R2 (64 bit) 

Database Server

SQL Server 2008 R2 (64 bit)

Windows Server 2003 SP1 (64 bit) 
Windows Server 2008 (64 bit) 
Windows Server 2008 R2 (64 bit)   

Server Virtualization

Hyper-V

Windows Server 2008 R2 (64 bit)
Bundled Server Components Windows Server 2003 SP1 (64 bit) 
Windows Server 2008 (64 bit) 
Windows Server 2008 R2 (64 bit) 
Integration Components
(see PTC documentation)

Windows Server 2003 SP1 (64 bit) 
Windows Server 2008 (64 bit) 
Windows Server 2008 R2 (64 bit) 

Windchill Archive Client Windows Server 2003 SP1 (64 bit) 
Windows Server 2008 (64 bit) 
Windows Server 2008 R2 (64 bit) 

Windchill 10.0 was released on April 4,2011. You may read further here.

Notes:

  • SQL Server 2008 must be cofigured with the correct collation: SQL_LATIN_1_General_CP1_CS_AS.
  • Version 10 will not install on SQL Server 2005.

Additional information from PTC on Windchill 10