> Plan antivirus scanning for Outlook 2010
- If you use antivirus software to perform file-level scanning [Outlook files], while Outlook is in use, data corruption issues might result.
- We we do not recommend that you scan *.pst, *.ost, and other Outlook files directly. Instead, we recommend that you scan email message attachments on the email server and on the Outlook client computer.
> Outlook 2007/2010 – More precisions about Antivirus exclusions and things that can slow down your messaging client in general