When I talk to customers, the different attacks are often something we discuss (obviously). I often mention that Virus and Worm attacks on a broad scale (like Conficker etc.) are a serious problem but at least one we see, one we understand and one we can fight (because we see and understand it).
However, my real concern are targeted attacks on governments and companies as they are incredibly hard to detect. In the last few months, every once in a while we read in the press about an attack on a government and sometimes they went undetected for months until either something happened like a server crashed or law enforcement found out somehow.
This morning I read an article which actually claims that the problem is even bigger than I thought: Report Details Hacks Targeting Google, Others – actually the article just uses the Google attacks to attract the readers as it does not really talk about it but the content is interesting nevertheless
I saw the wired article as well (blogged as you did) and I'm seeing more and more infections than ever before. It's sad to see that so many people are willing to take advantage of others in hopes of making a buck here and there.
I think the biggest issue right now is that nearly all AV/Antispyware is missing a lot of the Fake AV floating around right now. Maybe someon will get off their butt to help detect this stuff.
With regards to fake AV, there are different problems. Often tehy seem to be installing classical malware which is detected by classical AV-prevention. However, there are not too many different groups behind it but sometimes Law Enforcement in those countries does not care too much.
Having this said, LE does in the meantime a good job to go after the criminals. However, targeted attacks are not run by the groups spreading fake AV-software, it is run by people going for the big bucks