Our Support Engineer Eric E. on the Deployment Team, provided a great response to customers dealing with the enterprise deployment of the KB2543241 hotfix.  His post describes how to programmatically install the PowerPoint 2003 hotfix related to KB2543241 and KB2464588.

If you have installed the KB2464588 update for Microsoft PowerPoint 2003, which is related to Microsoft Security Bulletin MS11-022, you may be aware of/experiencing the following known issues:

When you open presentations that contain layouts with background images in PowerPoint 2003, an error may occur. When the error occurs, you receive a message that states that some contents (text, images, or objects) have corrupted. You can determine what content has been lost by viewing the layout, but not by viewing the slide content. Items that were removed will display a blank box or a box that contains "cleansed."

The KB2543241 hotfix was created to alleviate these issues.

See his post Office Deployment Support Team Blog: How to programmatically install the PowerPoint 2003 hotfix related to KB2543241 and KB2464588