I was doing an upgrade for a scale out deployment for SQL Reporting Services 2000 and the servers were having only 1 NIC. After the upgrade finished I found that the reporting services is not working as it was not initialized. Here are the details:
Reporting services is not initialized on both nodes with an error "can't connect to the database server" in the event viewer, accordingly the report generation stopped.
The encryption keys was corrupted on the reporting databases accordingly the nodes initialization can't succeed
Note: to be able to initialize the second node from the first node while NLB is enabled we have to create the below registry key to enable the InterHost communication while NLB is enabled and configured as Unicast KB898867.