http://blogs.technet.com/b/kdean/archive/2009/08/22/app-v-4-6-beta-now-available.aspxThis will be the first version of App-V to support both x64 and x86 Windows platforms.  The primary focus of this release is to enable App-V to take advantage of 64-bit Windows platforms including Windows 7 and Windows Server 2008 R2.  We’veen-USTelligent Evolution Platform Developer Build (Build: 5.6.50428.7875)