Now that Updates Publisher 2011 has released, you may ask yourself what do I need to do to install and configure.  Here is a high level to do list to help you get started.

1. Download Updates Publisher 2011 from here.  Note that Updates Publisher 2011 supports both ConfigMgr 2007 and ConfigMgr 2012 Beta2.
2. Download the required WSUS 3.0 SP2 hotfix here.
3. Install the WSUS 3.0 SP2 hotfix on all WSUS servers in your ConfigMgr hierarchy as well as your SCUP console computer
4. Install Updates Publisher 2011.  Updates Publisher 2011 does not upgrade from SCUP 4.5, but you can run them side-by-side.
1. Also note that SCUP requires administrator rights to install and will not prompt to elevate privileges.  The best way is to launch a command (cmd) prompt with “Run as Administrator” option then run the SystemCenterUpdatesPublisher.msi
5. Migrate all of your updates by exporting all of your updates from SCUP 4.5 and importing them into Updates Publisher 2011.
6. Open options dialog (upper right hand corner in blue) and enable checkbox for “Enable publishing to an update server”
1. Provide the same WSUS server you used with SCUP 4.5. 
2. The certificate used with SCUP 4.5 is still valid and if you install Updates Publisher 2011 on the same machine as SCUP 4.5 then you are done.
3. If SCUP 4.5 is installed on a different machine as Updates Publisher 2011 then you will need to add the signing certificate trust to the new machine as well.
7. Now everything is pretty much setup as before.
8. (Optional) Uninstall SCUP 4.5 after you are conformable with Updates Publisher 2011 and have all your updates migrated.

I hope this get everybody started, look for screencasts coming soon covering the entire product.