It's a question on the lips of businesses at the moment. As with most Microsoft-related information on the internet there are ample resources out there but picking and choosing the best ones is difficult.
Where would I start? Well, I think the Deployment Den I created a few weeks ago is a good place to find out the hot issues and answer common questions or concerns.
Then for the more technical amongst you the Desktop Deployment website is a good place for learning resources, field notes, UK events etc.
To get an overview of some of the tools available that can help you assess your hardware and software compatibility then check out the interview I recently did with deployment rock stars Richard Smith and Adam Shepherd - expect more of these over the coming weeks.