The simple answer is one (1). The sequencer is a single threaded application and will not take advantage of multi-core or multi-socket systems. Sequencer investments are better made in the disk I/O sub-system (see my item on disk performance).

In theory, sequencing on a machine with lots of background processes (for example, indexing, DWM, but not anti-virus) may perform slightly better on a multi-core machine as the sequencer thread will have access to a higher percentage of one of the cores, however, the sequencer is disk I/O intensive and it would be expected that this is where the most performance increase could be gained.

 

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