When you use the Refresh Server option to refresh a Publishing Server from the Microsoft Application Virtualization (App-V) Client MMC snap-in, you may receive the following error message:

The Application Virtualization Client could not update publishing information from the server ServerName.
No connection could be made because the target machine actively refused it.
Error code: xxxxxxx-xxxxxx2A-0000274D

This issue can occur if the App-V client cannot communicate with the Publishing Server.

For all the latest information including how to troubleshoot and resolve this issue see the following Knowledge Base article:

KB2266481 - Using the Refresh Server option to refresh a Publishing Server from the Microsoft Application Virtualization Client MMC snap-in results in error code 2A-0000274D

J.C. Hornbeck | System Center Knowledge Engineer